Research Interests
Research Interests:
2004-current
Direct Administration of Chemotherapy into the Fourth Ventricle for Treatment of Malignant Posterior Fossa Tumors of Childhood. Developing piglet model for direct infusions into the fourth ventricle.
2000-2002
Convection-Enhanced Delivery for the Treatment of Diffuse Pontine Gliomas. Demonstrated safety and determined distribution parameters for brain stem infusions in a rat model.
Publications:
Sandberg DI, Navarro R, Blanch J, Ragheb J. “Anomalous venous drainage preventing safe posterior fossa decompression in patients with Chiari malformation Type I and multisutural craniosynostosis.” J Neurosurgy (4 Suppl Pediatrics) 106: 490-494, 2007.
Trombly R, Sandberg DI, Wolfe SA, Ragheb J. “High-flow orbital arteriovenous malformation in a child: case report and review of current management options.” J Craniofacial Surgery 17(4): 779-782, 2006.
Nimmagadda A, Sandberg DI, Ragheb J. “Spontaneous involution of a large pineal region hemorrhagic cyst in an infant.” J Neurosurgy (4 Suppl Pediatrics) 104: 275-278, 2006.
Sandberg DI, McComb JG, Krieger MD. “Chemical analysis of fluid obtained from intracranial arachnoid cysts in pediatric patients.” J Neurosurg 5 Suppl Pediatrics) 103: 427-432, 2005.
Sandberg DI, McComb JG, Krieger MD. “Craniotomy for fenestration of multiloculated hydrocephalus in pediatric patients.” Neurosurgery 57 (1 Suppl.):100-106, 2005.
Sandberg DI, Ragheb J, Dunoyer D, Bhatia S, Olavarria G, Morrison G. “Surgical outcomes and seizure control rates after resection of dysembryoplastic neuroepithelial tumors.” Neurosurg Focus 18 (6a): E5, 2005.
Sandberg DI, Bilsky MH, Kushner BH, Souweidane MM, Kramer KK, Laquaglia MP, Panageas KS, Cheung NK-V. "Treatment of spinal involvement in neuroblastoma patients." Pediatric Neurosurgery 39 : 291-298, 2003.
Occhiogrosso G, Edgar MA, Sandberg DI, Souweidane MM. "Prolonged convection-enhanced delivery into the rat brainstem." Neurosurgery 52: 388-394, 2003.
Sandberg DI, Edgar MA, Souweidane MM. "Effect of hyperosmolar mannitol on convection-enhanced delivery into the rat brain stem." J Neuro-Oncology 58: 187-192, 2002.
Sandberg DI, Edgar MA, Souweidane MM. "Convection-enhanced delivery into the rat brain stem. " J Neurosurg 96: 885-891, 2002.
Sandberg DI, Lamberti-Pasculli M, Drake JM, Humphreys RP, Rutka JT. "Spontaneous intraparenchymal hemorrhage in full-term neonates." Neurosurgery 48: 1042-1049, 2001.
Sandberg DI, Edgar MA, Resch L, Rutka JT, Becker LE, Souweidane MM. "MIB-1 staining index of pediatric meningiomas." Neurosurgery 48: 590-597, 2001.
Bilsky MH, Schefler AC, Sandberg DI, Dunkel IJ, Rosenblum M. "Sclerosing epitheliod fibrosarcomas involving the neuraxis: report of three cases." Neurosurgery 47: 956-960, 2000.
Souweidane M, Sandberg D, Bilsky M, Gutin P. "Endoscopic biopsy of tumors of the third ventricle." Pediatr Neurosurg 33: 132-137, 2000.
Sandberg DI, Bilsky MH, Souweidane MM, Bzdil J, Gutin PH. "Ommaya reservoirs for the treatment of leptomeningeal metastases. Neurosurgery 47: 49-55, 2000.
Sandberg DI, Souweidane MM. "Hemifacial spasm caused by a pilocytic astrocytoma of the fourth ventricle." Pediatr Neurol 21: 754-756, 1999.
Sandberg DI, Souweidane MM. "Endoscopic-guided proximal catheter placement in treatment of posterior fossa cysts." Pediatr Neurosurg 30: 180-185, 1999.
Sandberg DI, Lavyne MH: "Symptomatic spinal epidural lipomatosis after local epidural steroid injections: case report.” Neurosurgery 45: 162-165, 1999.
Frucht DM, Sandberg DI, Brown MR, Gerstberger SM,
Holland SM. “IL-12-Independent costimulation pathways for interferon-gamma production in familial disseminated mycobacterium avium complex infection. Clin Immunol 91(2): 234-41, 1999.
Frucht DM, Yeung C, Sandberg D,
Holland SM. "Interleukin-12 deficiency in patients with familial disseminated mycobacterium avium complex infection." Journal of Investigative Medicine Suppl.43(2): 364A, 1995.
Presentations:
Bhatia S, Ragheb J, Sandberg DI, Morrison G, Jayakar P, Fernandez A, Lin WC. In vivo characterization of pediatric epileptogenic lesions using optical spectroscopy. American Association of Neurological Surgeons.
Washington, D.C. , 2007 (oral presentation).
Farhat H, Delgado AL, Salame J, Sandberg D, Bhatia S, Ragheb J, Zauner A. Safety and Efficacy of neuroendovascular procedures in children. American Association of Neurological Surgeons.
Washington, D.C. , 2007 (oral presentation).
Crandall, K, Kuluz J, Padgett K, Landrum J, Babino D, Petito CK, He D, Solano J, Gonzalez-Brito M, Sandberg DI. A Novel Method of Chemotherapy Delivery to the Fourth Ventricle. Eastern-Atlantic Student Research Forum.
Miami, FL , 2007 (oral presentation).
Sandberg DI, Morrison G, Bhatia S, Olavarria G, Ragheb J, Duchowny M, Jayakar P, Lin W-C. Optical characterization of pediatric brain tumors and epileptogenic lesions. AANS/CNS Section on Pediatric Neurological Surgery.
Orlando, FL , 2005 (oral presentation).
Berry C, Hoh DJ, Sandberg DI, Sosa IJ, Krieger MD, McComb JG. The use of cranial fixation pins in pediatric neurosurgery. Congress of Neurological Surgeons.
Boston, MA , 2005 (oral presentation).
Sandberg DI, McComb JG, Krieger MD. Craniotomy for multiloculated hydrocephalus in pediatric patients. AANS/CNS Section on Pediatric Neurological Surgery.
San Francisco, CA, 2004 (oral presentation).
Sandberg DI, McComb JG, Krieger MD. Chemical analysis of fluid obtained from intracranial Arachnoid cysts in pediatric patients. AANS/CNS Section on Pediatric Neurological Surgery.
San Francisco, CA , 2004 (oral presentation).
Heller C, Krieger MD, Sandberg DI, Oh BC, McComb JG. Program. AANS/CNS Section on Pediatric Neurological Surgery. Programmable versus fixed-pressure valves for the treatment of hydrocephalus in children.
San Francisco, CA , 2004 (oral presentation).
Sandberg DI, McComb JG, Krieger MD, Gilles FH. Why do arachnoid cysts enlarge? 32nd Annual Meeting of the International Society for Pediatric Neurosurgery. Buenos Aires, Argentina, 2004 (oral presentation).
Heller C, Krieger MD, Sandberg DI, Oh BC, McComb JG. Programmable versus fixed-pressure valves for the treatment of hydrocephalus in children. 32nd Annual Meeting of the International Society for Pediatric Neurosurgery. Buenos Aires, Argentina, 2004 (oral presentation).
Heller C, Krieger MD, Sandberg DI, Oh BC, McComb JG. Programmable versus fixed-pressure valves for the treatment of hydrocephalus in children. Congress of Neurological Surgeons. San
Francisco, CA , 2004 (oral presentation)
Oh BH, Krieger MD, Sandberg DI, Finlay J, McComb JG. "Neurofibromatosis 3 : A report of Patients meeting diagnostic criteria for both neurofibromatosis 1 and 2." International Symposium on Pediatric Neuro-Oncology.
Boston , MA 2004 (oral presentation).
Sandberg DI, Souweidane MM, Kushner BH,, Laquaglia MP, Bilsky MH, Kushner BH. "Treatment of spinal involvement in neuroblastoma patients." Congress of Neurological Surgeons.
Denver, Colorado , 2003 (oral presentation).
Ochiogrosso G, Sandberg D, Edgar M, Souweidane M. "Chronic brain stem infusion as a potential delivery system for diffuse pontine gliomas: an animal model. ” American Association of Neurological Surgeons.
Chicago, Illinois , 2002 (oral presentation)
Sandberg D, Edgar M, Souweidane M. “Convection-enhanced delivery into the rat brain stem: a potential delivery mechanism for the treatment of diffuse pontine gliomas.” American Association of Neurological Surgeons.
Chicago, Illinois , 2002 (oral presentation for Kenneth Shulman Award).
Sandberg D, Edgar M, Souweidane M. “Convection-enhanced delivery into the rat brain stem: a potential delivery mechanism for the treatment of diffuse pontine gliomas.” AANS/CNS Section on Pediatric Neurological Surgery.
New York, New York , 2001 (oral presentation).
Sandberg D, Edgar M, Souweidane M. "Convection-enhanced delivery into the brain stem: an animal model." Congress of Neurological Surgeons.
San Diego, California , 2001. (oral presentation).
Souweidane M, Sandberg D, Rutka J, Resch L, Edgar M. "MIB-1 staining index of pediatric meningiomas." AANS/CNS Section on Pediatric Neurological Surgery.
Atlanta , 1999. (oral presentation).
Souweidane M, Sandberg D, Bilsky M, Gutin P. "Endoscopic biopsy of tumors of the third ventricle." Congress of Neurological Surgeons.
Boston, Massachusetts , 1999. (oral poster presentation).
Sandberg D, Bilsky M, Souweidane M, Bzdil J, Gargan-Klinger R, Gutin P. "Ventricular access devices for leptomeningeal disease: techniques and complications." Congress of Neurological Surgeons.
Boston, Massachusetts , 1999. (poster presentation).
Sandberg D, Souweidane M. "Endoscopic-guided proximal catheter placement in treatment of posterior fossa cysts." AANS/CNS Section on Pediatric Neurological Surgery.
Indianapolis,
Indiana, 1998. (poster presentation).
Watts M, Sandberg D, Sills A, Bohan E, Gibbons C, Brem H. "Chemotherapeutic resistance patterns of tumor specimens from patients with glioblastoma multiforme and glioma cell lines. American Association of Neurological Surgeons.
Denver, Colorado , 1997. (poster presentation).
Sandberg D,
Watts M, Tyler B, Brem H. "Cytotoxicity of taxotere in vitro against human and rat malignant glioma cell lines." American Association of Neurological Surgeons.
Denver,
Colorado, 1997. (poster presentation)
Invited Presentations:
Hospital Escuela;
Tegucigalpa. “Neurosurgical residency training in the United States.” May, 2001.
Hospital Escuela;
Tegucigalpa. “Convection-enhanced delivery into the brain stem: an animal model.” May, 2001.
Hospital Escuela;
Tegucigalpa. “Contemporary management of hydrocephalus.” May, 2002.
Hospital Escuela;
Tegucigalpa. ”Management of open and closed neural tube defects.” May, 2002.
Symposium on Pediatric Neurosurgery,
New York
Presbyterian
Hospital ;
New York, NY. “Spinal dysraphism: definitions, diagnosis, and management. January, 2003.
Lima, Peru; Peruvian Neurosurgical Association. “Endoscopic management of hydrocephalus.” August, 2004.
Hospital Escuela;
Tegucigalpa. “Endoscopic management of hydrocephalus.” August, 2004.
Hospital Escuela;
Tegucigalpa. “Endoscopic management of brain tumors.” August, 2004.
Pediatric Neurosurgery Update, Miami Children's Hospital;
Miami, FL. “Spina Bifida Occulta – What's that on my Baby's Back?” November, 2004.
Grand Rounds, Department of Pediatrics,
University of
Miami;
Miami, FL. “Contemporary Management of Hydrocephalus” December, 2004.
Grand Rounds, Miami Children's Hospital;
Miami, FL. “Contemporary Management of Pediatric Brain Tumors.” January, 2005.
Grand Rounds, Department of Pediatrics,
Plantation General
Hospital;
Plantation, FL. “Contemporary Management of Pediatric Brain Tumors.” June, 2005.
Hospital Escuela;
Tegucigalpa, . “Contemporary Management of Pediatric Brain Tumors.” August, 2005.
Eleventh Annual Brain Injury Symposium; Wyndham Miami Beach Resort,
Miami Beach, FL. “Evaluation and Management of Pediatric Head Trauma.” October, 2005.
Florida Cleft Palate and Craniofacial (FCPA) Winter Symposium. “The Child with a Craniofacial Condition.”
Coral Gables, FL. January, 2007.
XVIII Annual Child Neurology Postgraduate Course, Miami Children's Hospital,
Miami, FL. “Advances in Neuroendoscopy.” May, 2007.
Seventh Hubert L. Rosomoff Research Day,
University of
Miami
School of
Medicine, Department of Neurological Surgery. “Direct Administration of Chemotherapy into the Fourth Ventricle: a Novel Therapeutic Approach for the Treatment of Malignant Posterior Fossa Tumors of Childhood. June, 2007.
Editorial Activities:
Ad hoc reviewer, Neurosurgical Focus, 2005, 2006.